Pub. Date : 2002 Oct
PMID : 12392591
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In human liver microsomes, a significant 2-fold decrease in the rate of hydroxycelecoxib formation was evident in CYP2C9*1/*3 samples compared with CYP2C9*1/*1 samples. | Hydroxy Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 2 | In human liver microsomes, a significant 2-fold decrease in the rate of hydroxycelecoxib formation was evident in CYP2C9*1/*3 samples compared with CYP2C9*1/*1 samples. | Hydroxy Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |
| 3 | There was also a marked reduction (up to 5.3 times) of hydroxycelecoxib formation in a liver sample genotyped as CYP2C9*3/*3. | Hydroxy Celecoxib | cytochrome P450 family 2 subfamily C member 9 | Homo sapiens |