Title : Neuropathy-specific analgesic action of intrathecal nicotinic agonists and its spinal GABA-mediated mechanism.

Pub. Date : 2002 Oct 25

PMID : 12384238






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 After antagonism experiments with mecamylamine, dihydro-beta-erythroidine and methyllycaconitine, it was observed that (-)nicotine-induced analgesia was mediated through the alpha4beta2 subtype of nAChR while the (+)epibatidine-induced one was mediated through non-alpha4beta2 subtype of nAChR. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 After antagonism experiments with mecamylamine, dihydro-beta-erythroidine and methyllycaconitine, it was observed that (-)nicotine-induced analgesia was mediated through the alpha4beta2 subtype of nAChR while the (+)epibatidine-induced one was mediated through non-alpha4beta2 subtype of nAChR. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus