Title : Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors.

Pub. Date : 2002 Oct

PMID : 12377393






1 Functional Relationships(s)
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1 These data suggest that acute amphetamine is able to facilitate the phosphorylation of CREB, Elk-1, and ERK1/2 signaling proteins and Fos gene expression via a group I mGluR-dependent mechanism in the dorsal striatum. Amphetamine Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus