Title : The role of O-linked protein glycosylation in beta-cell dysfunction.

Pub. Date : 2002 Nov

PMID : 12373287






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The diabetogenic agent streptozotocin (STZ), a UDP-GlcNAc analogue, causes beta-cell toxicity by irreversibly inhibiting O-GlcNAcase, while the diabetogenic agent alloxan (ALX), also a UDP-GlcNAc analog irreversibly inhibits OGT. Streptozocin O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 The diabetogenic agent streptozotocin (STZ), a UDP-GlcNAc analogue, causes beta-cell toxicity by irreversibly inhibiting O-GlcNAcase, while the diabetogenic agent alloxan (ALX), also a UDP-GlcNAc analog irreversibly inhibits OGT. Streptozocin O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens