Pub. Date : 2002 Oct 11
PMID : 12372399
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Prostaglandin F(2alpha) stimulates tyrosine phosphorylation of phospholipase C-gamma1. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
2 | In this study, we investigated the ability of prostaglandin F(2alpha) (PGF(2alpha)) to induce tyrosine phosphorylation of phospholipase C-gamma1 (PLC-gamma1) in cat iris sphincter smooth muscle (CISM) cells. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
3 | In this study, we investigated the ability of prostaglandin F(2alpha) (PGF(2alpha)) to induce tyrosine phosphorylation of phospholipase C-gamma1 (PLC-gamma1) in cat iris sphincter smooth muscle (CISM) cells. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
4 | PGF(2alpha)(1 microM) stimulated PLC-gamma1 tyrosine phosphorylation in a time- and dose-dependent manner with a maximum increase of 3-fold at 0.5min. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
5 | In summary, these findings show that PGF(2alpha) stimulates tyrosine phosphorylation of PLC-gamma1 in CISM cells and indicate that PGF(2alpha)-stimulated tyrosine phosphorylation is responsible for an early signal transduction event. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |
6 | In summary, these findings show that PGF(2alpha) stimulates tyrosine phosphorylation of PLC-gamma1 in CISM cells and indicate that PGF(2alpha)-stimulated tyrosine phosphorylation is responsible for an early signal transduction event. | Tyrosine | phospholipase C gamma 1 | Homo sapiens |