Title : Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering.

Pub. Date : 2002 Nov

PMID : 12371961






1 Functional Relationships(s)
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1 The effects of simvastatin were prevented in the presence of mevalonate and geranylgeraniol, suggesting that the effect of simvastatin on t-PA and PAI-1 synthesis is mediated through geranylgeranyl-modified intermediates. Mevalonic Acid serpin family E member 1 Homo sapiens