Title : Stimulation of the Raf/MEK/ERK cascade is necessary and sufficient for activation and Thr-160 phosphorylation of a nuclear-targeted CDK2.

Pub. Date : 2002 Dec 6

PMID : 12359725






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Activation of CDK2 requires the removal of two inhibitory phosphates (Thr-14 and Tyr-15) and the addition of one activating phosphate (Thr-160) by a nuclear localized CDK-activating kinase, which is thought to be constitutively active. Phosphates cyclin dependent kinase 2 Homo sapiens
2 Activation of CDK2 requires the removal of two inhibitory phosphates (Thr-14 and Tyr-15) and the addition of one activating phosphate (Thr-160) by a nuclear localized CDK-activating kinase, which is thought to be constitutively active. Phosphates cyclin dependent kinase 2 Homo sapiens