Title : Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan.

Pub. Date : 2002 Aug

PMID : 12358797






1 Functional Relationships(s)
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1 In mitochondria isolated from rat liver, NM(R)Sal induced swelling and reduced DeltaPsim, which was inhibited by cyclosporin A and Bcl-2 overexpression. sal BCL2, apoptosis regulator Rattus norvegicus