Pub. Date : 2002 Sep 27
PMID : 12270144
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of Mg(2+) on the kinetics of guanine nucleotide binding and hydrolysis by Cdc42. | magnesium ion | cell division cycle 42 | Homo sapiens |
| 2 | In contrast to the cases of Ras and Rab proteins, which require Mg(2+) for the nucleotide binding and intrinsic hydrolysis of GTP, our results show that in the absence of Mg(2+), the binding affinity of GTP to Cdc42 is in the submicromolar concentration, and the Mg(2+) cofactor has only a minor effect on the Cdc42-catalyzed intrinsic hydrolysis rate of GTP. | magnesium ion | cell division cycle 42 | Homo sapiens |