Title : T cell apoptosis by tryptophan catabolism.

Pub. Date : 2002 Oct

PMID : 12232795






1 Functional Relationships(s)
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1 We show here that tryptophan metabolites in the kynurenine pathway, such as 3-hydroxyanthranilic and quinolinic acids, will induce the selective apoptosis in vitro of murine thymocytes and of Th1 but not Th2 cells. Kynurenine heart and neural crest derivatives expressed 2 Mus musculus