Title : Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators.

Pub. Date : 2002 Sep

PMID : 12204894






1 Functional Relationships(s)
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1 Using Western blot analysis and in vitro kinase assays, we found that dexamethasone results in decreased activity of CDK2 and 4, decreased levels of cyclin D, E2F, and Myc, and increased levels of the CDK inhibitor p21(Cip1). Dexamethasone cyclin dependent kinase 2 Homo sapiens