Pub. Date : 2002 Aug 27
PMID : 12196343
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: The nature of some of the target genes for liver X receptors (LXRs)-alpha and -beta, such as sterol regulatory element binding protein-1 and ATP-binding cassette transporter proteins, suggests a pivotal role of these nuclear receptors in the regulation of fatty acid and cholesterol homeostasis. | Cholesterol | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 2 | The combined deficiency of LXRalpha and LXRbeta was linked to impaired triglyceride metabolism, increased LDL and reduced HDL cholesterol levels, and cholesterol accumulation in macrophages (foam cells) of the spleen, lung, and arterial wall. | Cholesterol | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |
| 3 | The combined deficiency of LXRalpha and LXRbeta was linked to impaired triglyceride metabolism, increased LDL and reduced HDL cholesterol levels, and cholesterol accumulation in macrophages (foam cells) of the spleen, lung, and arterial wall. | Cholesterol | nuclear receptor subfamily 1, group H, member 3 | Mus musculus |