Title : Regulation of connexin 43 by nitric oxide in primary uterine myocytes from term pregnant women.

Pub. Date : 2002 Aug

PMID : 12193939






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Regulation of connexin 43 by nitric oxide in primary uterine myocytes from term pregnant women. Nitric Oxide gap junction protein alpha 1 Homo sapiens
2 OBJECTIVE: Our purpose was to test the hypothesis that nitric oxide signals regulate the expression of the gap-junction protein connexin 43 in primary uterine myocytes from pregnant women at term. Nitric Oxide gap junction protein alpha 1 Homo sapiens
3 RESULTS: Nitric oxide and 8-bromo-cAMP reduced the level of connexin 43 expression, and 8-bromo-cGMP had no effect. Nitric Oxide gap junction protein alpha 1 Homo sapiens
4 CONCLUSION: Nitric oxide down-regulates the expression of connexin 43 in cultured human myocytes. Nitric Oxide gap junction protein alpha 1 Homo sapiens