Title : A population phenotyping study of three drug-metabolizing enzymes in Kyushu, Japan, with use of the caffeine test.

Pub. Date : 2002 Aug

PMID : 12189367






1 Functional Relationships(s)
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1 CONCLUSIONS: Our results suggest that putative poor metabolizers of xanthine oxidase activities exist in a Japanese population and that a decreased 1,7-dimethyluric acid formation from caffeine in poor metabolizers of CYP2A6 appears to affect the metabolic ratio used for the assessment of CYP1A2 activity. Caffeine cytochrome P450 family 2 subfamily A member 6 Homo sapiens