PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12189367-9 2002 CONCLUSIONS: Our results suggest that putative poor metabolizers of xanthine oxidase activities exist in a Japanese population and that a decreased 1,7-dimethyluric acid formation from caffeine in poor metabolizers of CYP2A6 appears to affect the metabolic ratio used for the assessment of CYP1A2 activity. Caffeine 185-193 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 218-224