Pub. Date : 2002 Feb
PMID : 12187485
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Based on this, we hypothesized that folate would enter the RPE via FR alpha and exit the cell via RFT-1. | Folic Acid | FOS like 1, AP-1 transcription factor subunit | Homo sapiens |
| 2 | The presence of FR alpha in the basal membrane was demonstrable by folate binding and that of RFT-1 in the apical membrane by blockade of folate transport by RFT-1-specific antibody. | Folic Acid | FOS like 1, AP-1 transcription factor subunit | Homo sapiens |
| 3 | The presence of FR alpha in the basal membrane was demonstrable by folate binding and that of RFT-1 in the apical membrane by blockade of folate transport by RFT-1-specific antibody. | Folic Acid | FOS like 1, AP-1 transcription factor subunit | Homo sapiens |
| 4 | This study represents the first in vitro demonstration of transcellular transfer of folate across RPE and suggests that folate is transported from the choriocapillaris to the adjacent photoreceptor cells in vivo by the concerted action of FR alpha in the basal membrane and RFT-1 in the apical membrane. | Folic Acid | FOS like 1, AP-1 transcription factor subunit | Homo sapiens |