Title : Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon.

Pub. Date : 2002 Sep

PMID : 12183516






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Examination of the ability of splenocytes from uninfected and infected mice to produce IFN-gamma revealed that IL-2(-/-) mice were hyporesponsive to stimulation with anti-CD3 or parasite antigen compared with wild-type mice, and the addition of IL-2 alone or in combination with IL-12 or stimulation with phorbol myristate acetate and ionomycin did not restore the production of IFN-gamma. Ionomycin interleukin 2 Mus musculus