Title : Ca2+- and PKC-dependent stimulation of PGE2 synthesis by deoxycholic acid in human colonic fibroblasts.

Pub. Date : 2002 Sep

PMID : 12181161






1 Functional Relationships(s)
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1 Increases in PGE2 synthesis were preceded by sequential increases in PGH synthase-2 mRNA and protein expression and were fully prevented by a nonselective (indomethacin) or a selective (celecoxib) nonsteroidal anti-inflammatory drug. Indomethacin prostaglandin-endoperoxide synthase 2 Homo sapiens