Pub. Date : 2002 Jul-Aug
PMID : 12140351
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Trait anxiety and tamoxifen effects on bone mineral density and sex hormone- binding globulin. | Tamoxifen | sex hormone binding globulin | Homo sapiens |
| 2 | OBJECTIVE: Tamoxifen therapy preserves BMD of the lumbar spine and increases levels of SHBG. | Tamoxifen | sex hormone binding globulin | Homo sapiens |
| 3 | We assessed whether trait anxiety, a factor linked with a reactive endocrine system, is associated with differential changes in BMD and SHBG levels in response to tamoxifen therapy. | Tamoxifen | sex hormone binding globulin | Homo sapiens |
| 4 | High anxiety also was associated with lower levels of SHBG for women using tamoxifen at 3, 12, 18, and 24 months (p values <.05). | Tamoxifen | sex hormone binding globulin | Homo sapiens |
| 5 | CONCLUSIONS: Trait anxiety is associated with greater preservation of lumbar spine BMD in response to tamoxifen and with a suppression of tamoxifen-induced increases in SHBG. | Tamoxifen | sex hormone binding globulin | Homo sapiens |