Pub. Date : 2002
PMID : 12127941
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 4-hydroxyphenylpyruvate dioxygenase (HPD) (EC 1.13.11.27) is a key enzyme involved in tyrosine catabolism. | Tyrosine | 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens |
| 2 | 4-hydroxyphenylpyruvate dioxygenase (HPD) (EC 1.13.11.27) is a key enzyme involved in tyrosine catabolism. | Tyrosine | 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens |
| 3 | The severe type I tyrosinemia, caused by a deficiency of fumarylacetoacetate hydrolase which functions downstream of HPD in the tyrosine degradation pathway, is often associated with decreased expression of HPD, and interestingly, inhibition of HPD activity seems to ameliorate the clinical symptoms of type I tyrosinemia. | Tyrosine | 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens |
| 4 | The severe type I tyrosinemia, caused by a deficiency of fumarylacetoacetate hydrolase which functions downstream of HPD in the tyrosine degradation pathway, is often associated with decreased expression of HPD, and interestingly, inhibition of HPD activity seems to ameliorate the clinical symptoms of type I tyrosinemia. | Tyrosine | 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens |
| 5 | The severe type I tyrosinemia, caused by a deficiency of fumarylacetoacetate hydrolase which functions downstream of HPD in the tyrosine degradation pathway, is often associated with decreased expression of HPD, and interestingly, inhibition of HPD activity seems to ameliorate the clinical symptoms of type I tyrosinemia. | Tyrosine | 4-hydroxyphenylpyruvate dioxygenase | Homo sapiens |