Pub. Date : 2002 Jun 18
PMID : 12126567
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVE: To investigate the effects of macrophage colony-stimulating factor (M-CSF) on estradiol and progesterone production by human luteinized granulosa cells in vitro and to detect M-CSF receptor in human granulosa cells. | Estradiol | colony stimulating factor 1 | Homo sapiens |
2 | OBJECTIVE: To investigate the effects of macrophage colony-stimulating factor (M-CSF) on estradiol and progesterone production by human luteinized granulosa cells in vitro and to detect M-CSF receptor in human granulosa cells. | Estradiol | colony stimulating factor 1 | Homo sapiens |
3 | Thus M-CSF caused a significant dose dependent increase of estradiol and progesterone production (P < 0.05), and M-CSF+ FSH further stimulated higher production of E(2) and P by LGC than M-CSF or FSH alone (P < 0.05). | Estradiol | colony stimulating factor 1 | Homo sapiens |
4 | M-CSF enhances estradiol and progesterone production by LGC and FSH has an additional or synergetic effect with M-CSF. | Estradiol | colony stimulating factor 1 | Homo sapiens |