Title : Role of retinoblastoma protein and E2F-1 transcription factor in the acquisition of 5-fluorouracil resistance by colon cancer cells.

Pub. Date : 2002 Aug

PMID : 12118326






1 Functional Relationships(s)
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1 These results suggested that pRb and E2F-1 play important roles in the acquisition of 5-FU resistance by cancer cells and that cancer therapy targeting transcription factor E2F might be effective. Fluorouracil RB transcriptional corepressor 1 Homo sapiens