Title : Modulation of irinotecan metabolism by ketoconazole.

Pub. Date : 2002 Jul 15

PMID : 12118026






2 Functional Relationships(s)
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1 CONCLUSION: Inhibition of CYP3A4 in cancer patients treated with irinotecan leads to significantly increased formation of SN-38. Irinotecan cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 CONCLUSION: Inhibition of CYP3A4 in cancer patients treated with irinotecan leads to significantly increased formation of SN-38. Irinotecan cytochrome P450 family 3 subfamily A member 4 Homo sapiens