Pub. Date : 2002 Sep 20
PMID : 12118006
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, like insulin, EGCG increases tyrosine phosphorylation of the insulin receptor and insulin receptor substrate-1 (IRS-1), and it reduces phosphoenolpyruvate carboxykinase gene expression in a phosphoinositide 3-kinase-dependent manner. | epigallocatechin gallate | insulin | Homo sapiens |
| 2 | Furthermore, like insulin, EGCG increases tyrosine phosphorylation of the insulin receptor and insulin receptor substrate-1 (IRS-1), and it reduces phosphoenolpyruvate carboxykinase gene expression in a phosphoinositide 3-kinase-dependent manner. | epigallocatechin gallate | insulin | Homo sapiens |
| 3 | Furthermore, like insulin, EGCG increases tyrosine phosphorylation of the insulin receptor and insulin receptor substrate-1 (IRS-1), and it reduces phosphoenolpyruvate carboxykinase gene expression in a phosphoinositide 3-kinase-dependent manner. | epigallocatechin gallate | insulin | Homo sapiens |
| 4 | EGCG also mimics insulin by increasing phosphoinositide 3-kinase, mitogen-activated protein kinase, and p70(s6k) activity. | epigallocatechin gallate | insulin | Homo sapiens |
| 5 | EGCG differs from insulin, however, in that it affects several insulin-activated kinases with slower kinetics. | epigallocatechin gallate | insulin | Homo sapiens |