Pub. Date : 2002 Jul 1
PMID : 12089223
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918. | Topotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | CONCLUSION: Coadministration of the BCRP and P-gp inhibitor GF120918 resulted in a significant increase of the systemic exposure of oral topotecan. | Topotecan | ATP binding cassette subfamily B member 1 | Homo sapiens |