Pub. Date : 2002 Jul 1
PMID : 12089223
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PURPOSE: We discovered that breast cancer resistance protein (BCRP), a recently identified adenosine triphosphate-binding cassette drug transporter, substantially limits the oral bioavailability of topotecan in mdr1a/1b(-/-) P-glycoprotein (P-gp) knockout and wild-type mice. | Topotecan | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |
| 2 | PURPOSE: We discovered that breast cancer resistance protein (BCRP), a recently identified adenosine triphosphate-binding cassette drug transporter, substantially limits the oral bioavailability of topotecan in mdr1a/1b(-/-) P-glycoprotein (P-gp) knockout and wild-type mice. | Topotecan | ATP binding cassette subfamily G member 2 (Junior blood group) | Mus musculus |