Title : In vitro and in vivo characterisation of [11C]-DASB: a probe for in vivo measurements of the serotonin transporter by positron emission tomography.

Pub. Date : 2002 Jul

PMID : 12088720






1 Functional Relationships(s)
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1 Ex vivo, [11C]-DASB binding in rat brain was shown to be saturable (ED(50) of 56 nmoles/kg), and sensitive to both the number of available SERT binding sites and the number of viable serotonin neurons. 3-amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile solute carrier family 6 member 4 Rattus norvegicus