Title : Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats.

Pub. Date : 2002 Jun

PMID : 12079509






1 Functional Relationships(s)
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1 Concomitant administration of 2% or 0.2% bLF with MeIQx caused significant dose-dependent decreases in both number and unit area of GST-P(+) cell foci (2% bLF, P < 0.001; 0.2% bLF, P < 0.01). 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline glutathione S-transferase pi 1 Rattus norvegicus