Pub. Date : 2002 Jul 1
PMID : 12071842
3 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Recently we identified lipomannan and mannosylated lipoarabinomannan (ManLAM), two major mycobacterial cell-wall lipoglycans, as potential ligands for binding of hSP-A. | manlam | surfactant protein A1 | Homo sapiens | ||
| 2 | Binding of ManLAM to immobilized hSP-A was consistent with the simplest one-to-one interaction model involving a single class of carbohydrate-binding site. | manlam | surfactant protein A1 | Homo sapiens | ||
| 3 | This observation strongly suggests that the lipid moiety of ManLAM does not directly interact with hSP-A, but is rather responsible for the macromolecular organization of the lipoglycan, which may be necessary for efficient recognition of the terminal mannosyl epitopes. | manlam | surfactant protein A1 | Homo sapiens | ||