Title : Activation of retinoic acid receptor-dependent transcription by all-trans-retinoic acid metabolites and isomers.

Pub. Date : 2002 Aug 30

PMID : 12070176






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 For RAR beta, the EC(50) values increased as follows: 4-oxo-RA (8 nM), ATRA (9 nM), 18-OH-RA (14 nM), 5,6-epoxy-RA (35 nM), 13-cis-RA (47 nM), 4-OH-RA (64 nM), and 9-cis-RA (173 nM). Tretinoin retinoic acid receptor beta Homo sapiens
2 For RAR beta, the EC(50) values increased as follows: 4-oxo-RA (8 nM), ATRA (9 nM), 18-OH-RA (14 nM), 5,6-epoxy-RA (35 nM), 13-cis-RA (47 nM), 4-OH-RA (64 nM), and 9-cis-RA (173 nM). Tretinoin retinoic acid receptor beta Homo sapiens