Title : A non-amyloidogenic function of BACE-2 in the secretory pathway.

Pub. Date : 2002 Jun

PMID : 12065613






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Radiosequencing of the membrane-bound C-terminal cleavage product revealed that BACE-2 cleaves betaAPP in the middle of the Abeta domain between phenylalanines 19 and 20, resulting in increased secretion of APPs-alpha- and p3-like products and reduced production of Abeta species. Phenylalanine beta-secretase 2 Homo sapiens