Title : Protein kinase C-epsilon mediates phorbol ester-induced phosphorylation of connexin-43.

Pub. Date : 2001

PMID : 12064598






3 Functional Relationships(s)
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1 Stimulation of cardiomyocytes with phorbol 12-myristate 13-acetate (PMA) increased the fraction of the slower migrating (> or = 45 kDa) and more extensively phosphorylated Cx43 species. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens
2 Stimulation of cardiomyocytes with phorbol 12-myristate 13-acetate (PMA) increased the fraction of the slower migrating (> or = 45 kDa) and more extensively phosphorylated Cx43 species. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens
3 Selective inhibition of PKCE significantly decreased baseline levels of Cx43 phosphorylation and the PMA-induced accumulation of > or = 45 kDa Cx43. Tetradecanoylphorbol Acetate gap junction protein alpha 1 Homo sapiens