Title : Apoptosis during ectromelia orthopoxvirus infection is DEVDase dependent: in vitro and in vivo studies.

Pub. Date : 2002 May

PMID : 12048029






1 Functional Relationships(s)
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1 Here, we report that EV can regulate apoptosis in vitro, suppressing the activity of caspases recognizing the DEVD (Asp-Glu-Val-Asp) motif (caspase-3 and -7) before successful virus replication is completed. DEVD caspase 3 Mus musculus