Title : Effects of tamoxifen on human squamous cell carcinoma lines of the head and neck.

Pub. Date : 2002 Jun

PMID : 12045464






2 Functional Relationships(s)
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1 TAM caused decreased TGF-alpha and increased TGF-beta levels in MCF-7, but not in SCCHN supernatants. Tamoxifen transforming growth factor alpha Homo sapiens
2 In the present in vitro system, the observed antitumor activity of high-dose TAM in SCCHN cannot be explained by estrogen antagonism, alterations of TGF-alpha/beta levels or decreased PKC activity. Tamoxifen transforming growth factor alpha Homo sapiens