Title : Inactivation and degradation of O(6)-alkylguanine-DNA alkyltransferase after reaction with nitric oxide.

Pub. Date : 2002 Jun 1

PMID : 12036910






1 Functional Relationships(s)
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Protein Name
Organism
1 The facile reaction of this cysteine residue with NO is attributable to its interaction with other residues in hAGT including His-146 and Glu-172 that activate the sulfhydryl group of Cys-145 to allow its nucleophilic attack on DNA adducts. Histidine angiotensinogen Homo sapiens