Title : IL-7 withdrawal induces a stress pathway activating p38 and Jun N-terminal kinases.

Pub. Date : 2002 Sep

PMID : 12034357






1 Functional Relationships(s)
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1 Induction of jun and fos genes and the increased DNA-binding activity of AP-1 were attributable to the phosphorylation-induced activation of the stress kinases p38 and JNK and were blocked by the chemical kinase inhibitors SB203580 and SB202190. 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole mitogen-activated protein kinase 8 Homo sapiens