Title : IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice.

Pub. Date : 2002 May

PMID : 12010781






3 Functional Relationships(s)
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1 In wildtype mice, inhibition of p38 or ERK1/2 MAPKs significantly reduced IL-1beta induced IL-6 release, whilst the NFkappaB inhibitor caffeic acid phenethyl ester (CAPE) modulated IL-1 induced IL-6 release by action on NFkappaB and MAPKs pathways. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 In wildtype mice, inhibition of p38 or ERK1/2 MAPKs significantly reduced IL-1beta induced IL-6 release, whilst the NFkappaB inhibitor caffeic acid phenethyl ester (CAPE) modulated IL-1 induced IL-6 release by action on NFkappaB and MAPKs pathways. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 In wildtype mice, inhibition of p38 or ERK1/2 MAPKs significantly reduced IL-1beta induced IL-6 release, whilst the NFkappaB inhibitor caffeic acid phenethyl ester (CAPE) modulated IL-1 induced IL-6 release by action on NFkappaB and MAPKs pathways. caffeic acid phenethyl ester nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus