Pub. Date : 2002 May 8
PMID : 11982363
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Development of a novel method to populate native disulfide-bonded intermediates for structural characterization of proteins: implications for the mechanism of oxidative folding of RNase A. | Disulfides | ribonuclease A family member 1, pancreatic | Homo sapiens |
| 2 | RNase A, a model protein for oxidative folding studies, has four native disulfide bonds. | Disulfides | ribonuclease A family member 1, pancreatic | Homo sapiens |
| 3 | The application of this method enabled us to populate and, in turn, study the key intermediates with two native disulfide bonds on the oxidative folding pathway of RNase A; it also facilitated the isolation of des [58-110] and des [26-84], the other two native-like structured des species whose isolation had thus far not been possible. | Disulfides | ribonuclease A family member 1, pancreatic | Homo sapiens |