Title : Isoproterenol inhibits transcription of cardiac cytokine genes induced by reactive oxygen intermediates.

Pub. Date : 2002 Apr

PMID : 11964604






3 Functional Relationships(s)
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1 Simultaneous infusion of isoproterenol inhibited TNF-alpha and interleukin-6 release. Isoproterenol tumor necrosis factor Rattus norvegicus
2 Inclusion of propranolol in the perfusion buffer blocked the isoproterenol-induced inhibition of HX-XO-stimulated TNF-alpha release and release of cyclic AMP into the coronary effluent. Isoproterenol tumor necrosis factor Rattus norvegicus
3 Finally, delaying infusion of isoproterenol until 30 min after HX-XO administration still suppressed release of TNF-alpha. Isoproterenol tumor necrosis factor Rattus norvegicus