Title : Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein.

Pub. Date : 2002 Apr

PMID : 11964599






2 Functional Relationships(s)
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1 Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. Alfentanil ATP binding cassette subfamily B member 1 Homo sapiens
2 Loperamide, sufentanil, fentanyl, and alfentanil inhibited P-glycoprotein-mediated digoxin transport in Caco-2 cells with IC50 values of 2.5, 4.5, 6.5, and 112 microm, respectively. Alfentanil ATP binding cassette subfamily B member 1 Homo sapiens