Title : Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner.

Pub. Date : 2002 Apr 16

PMID : 11960023






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The N-terminal cytoplasmic domain of GAT1 directly interacts with syntaxin 1A; this interaction induces a decrease in the rate at which GABA and associated ions are transported. gamma-Aminobutyric Acid syntaxin 1A Rattus norvegicus
2 These data suggest that substrate translocation regulates GAT1-syntaxin 1A interactions and provide a mechanism by which GABA transport can be increased during times of rising synaptic GABA concentrations. gamma-Aminobutyric Acid syntaxin 1A Rattus norvegicus
3 These data suggest that substrate translocation regulates GAT1-syntaxin 1A interactions and provide a mechanism by which GABA transport can be increased during times of rising synaptic GABA concentrations. gamma-Aminobutyric Acid syntaxin 1A Rattus norvegicus