Pub. Date : 2002 May
PMID : 11956159
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using inhibitors of serine/threonine phosphatase activity (okadaic acid) and phosphotyrosine phosphatase activity (peroxyvanadate), we can inhibit the cAMP-inducible binding of the steroidogenic factor-1 (SF-1), p54(nrb)/NonO, and polypyrimidine tract-binding protein-associated splicing factor (PSF) complex required for regulation of transcription to the promoter of hCYP17. | Okadaic Acid | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
2 | Further, both okadaic acid and peroxyvanadate attenuate cAMP-stimulated increases in endogenous hCYP17 mRNA expression and in hCYP17 promoter-reporter construct luciferase activity. | Okadaic Acid | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
3 | Further, both okadaic acid and peroxyvanadate attenuate cAMP-stimulated increases in endogenous hCYP17 mRNA expression and in hCYP17 promoter-reporter construct luciferase activity. | Okadaic Acid | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |