Title : Role of nitric oxide and peroxynitrite in gut barrier failure.

Pub. Date : 2002 Jul

PMID : 11948371






1 Functional Relationships(s)
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1 Evidence suggests that sustained upregulation of the inducible isoform of nitric oxide synthase (NOS-2) co-localizes with enterocyte apoptosis and immunoreactivity to 3-nitrotyrosine, the footprint of peroxynitrite (ONOO-), a potent oxidant formed by the reaction of nitric oxide (NO) with superoxide. 3-nitrotyrosine nitric oxide synthase 2 Homo sapiens