Title : cAMP response element-binding protein is essential for the upregulation of brain-derived neurotrophic factor transcription, but not the behavioral or endocrine responses to antidepressant drugs.

Pub. Date : 2002 Apr 15

PMID : 11943827






3 Functional Relationships(s)
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1 Furthermore, the ability of DMI to suppress an acute corticosterone response after swim stress is maintained in CREB-deficient mice. Desipramine cAMP responsive element binding protein 1 Mus musculus
2 However, upregulation of a molecular target of CREB, BDNF, is abolished in the CREB-deficient mice after chronic administration of DMI. Desipramine cAMP responsive element binding protein 1 Mus musculus
3 However, upregulation of a molecular target of CREB, BDNF, is abolished in the CREB-deficient mice after chronic administration of DMI. Desipramine cAMP responsive element binding protein 1 Mus musculus