Title : Folate targeting of haptens to cancer cell surfaces mediates immunotherapy of syngeneic murine tumors.

Pub. Date : 2002 May

PMID : 11941454






2 Functional Relationships(s)
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1 Thus, using M109 syngeneic lung cancer cells injected intraperitoneally into Balb/c mice that were previously immunized against fluorescein, a significant extension of life span is observed following treatment with folate-fluorescein conjugates, and complete cures are observed upon supplementation with moderate levels of IL-2 and IFN-alpha. Fluorescein interleukin 2 Mus musculus
2 Thus, using M109 syngeneic lung cancer cells injected intraperitoneally into Balb/c mice that were previously immunized against fluorescein, a significant extension of life span is observed following treatment with folate-fluorescein conjugates, and complete cures are observed upon supplementation with moderate levels of IL-2 and IFN-alpha. Fluorescein interleukin 2 Mus musculus