Title : Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3).

Pub. Date : 2002 Jun 14

PMID : 11934890






3 Functional Relationships(s)
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Protein Name
Organism
1 Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3). Dehydroepiandrosterone succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens
2 DHEA stimulated [35S]GTPgammaS binding to Galpha(i2) and Galpha(i3), but not to Galpha(i1) or Galpha(o). Dehydroepiandrosterone succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens
3 Pretreatment of plasma membranes with antibody to Galpha(i2) or Galpha(i3), but not to Galpha(i1), inhibited the DHEA activation of eNOS. Dehydroepiandrosterone succinate-CoA ligase GDP/ADP-forming subunit alpha Homo sapiens