Title : Syk regulation of phosphoinositide 3-kinase-dependent NK cell function.

Pub. Date : 2002 Apr 1

PMID : 11907067






1 Functional Relationships(s)
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1 Inhibition of Syk function by kinase-deficient Syk or piceatannol blocked target cell-induced PI3K, Rac1, PAK1, mitogen-activated protein/ERK kinase, and ERK activation, perforin movement, as well as NK cytotoxicity, indicating that Syk is upstream of all these signaling events. 3,3',4,5'-tetrahydroxystilbene spleen associated tyrosine kinase Homo sapiens