Title : Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases.

Pub. Date : 2002 May 24

PMID : 11893743






1 Functional Relationships(s)
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1 Through the use of mass spectrometry, rapid quenching techniques, and NMR structural analyses, 2"-O-acetyl-ADP-ribose and 3"-O-acetyl-ADP-ribose were found to be the solution products produced by the Sir2 family of enzymes. 2-O-acetyl-ADP-ribose sirtuin 2 Homo sapiens