Title : The protein kinase B/Akt signalling pathway in human malignancy.

Pub. Date : 2002 May

PMID : 11882383






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 PI-3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP(3)), a lipid second messenger essential for the translocation of PKB/Akt to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1) and possibly other kinases. pip(3) pyruvate dehydrogenase kinase 1 Homo sapiens
2 PI-3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP(3)), a lipid second messenger essential for the translocation of PKB/Akt to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1) and possibly other kinases. pip(3) pyruvate dehydrogenase kinase 1 Homo sapiens