Title : Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.

Pub. Date : 2002 Feb 28

PMID : 11882343






1 Functional Relationships(s)
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1 Lesch-Nyhan disease, a neurogenetic disorder caused by congenital deficiency of the purine salvage enzyme hypoxanthine guanine phosphoribosyl transferase, is associated with a prominent loss of striatal dopamine. Dopamine hypoxanthine guanine phosphoribosyl transferase Mus musculus